Mary: Missy, don't forget that you have to pick out a present for that birthday next week.
Missy: Mom, it's "Melissa" now.
Mary: [to Brenda] Middle school.

Missy: Eat dirt. Eat it.
Meemaw: Kick his ass!
Missy: Does it taste good? Huh?
Dale: Yeah, listen to your meemaw. Kick his ass!
Missy: You gonna cry? Huh? Do it. Cry.
Mary: Do something. Break it up.
George Sr.: H-Hang on. She's winning.
Mary: Missy! Missy Cooper, you stop beating up that boy!
Meemaw: Punch him in the nuts!

Missy: Someone's Underoos are in a knot.
Sheldon: My Underoos are fitting just fine, thank you.
Missy: Then why is there a stick up your butt?
Sheldon: Stop making inquiries about my bottom.
Missy: But I enjoy it.

[Sheldon sits on the top of the couch with his feet on the cushion]
Missy: What are you doing?
Sheldon: I'm practicing the philosophy of cynicism... The ancient Greek view that the rules of society should be ignored.
Missy: If you're gonna break rules, you can do better than that.
Sheldon: How?
[Missy pushes Sheldon off the couch]

Billy Sparks: Who's Melissa?
Missy: Me.
Billy Sparks: Then who's Missy?
Missy: "Missy" is short for "Melissa." Like how "Billy" is short for "William."
Billy Sparks: I don't understand.
Missy: You know how your real name is William?
Billy Sparks: I'm Billy.
Sheldon: No, we call you Billy, but your real name is William.
Billy Sparks: But my underpants say "Billy" in them. Mom, is my name William?
Brenda Sparks: [sighs] Yeah.
Billy Sparks: Then whose underpants am I wearing?

Pastor Jeff: Two months! Two months till this baby comes! There's so much I thought I was gonna do in my life.
George Sr.: I'm sure you've done plenty.
Pastor Jeff: Nothing cool. Look at you. You played football and rode a motorcycle.
George Sr.: Well, you save people's souls. That's neat, right?
Pastor Jeff: Oh, it's neat as neat can be, but you know that's not what I'm talking about.
George Sr.: [sighs] Look, being a dad doesn't mean your life is over. It just means it's different. Instead of playing football, I get to coach it now. I mean, high school football. Not college like I'd hoped. I-Instead of a motorcycle, I drive a truck. To work every single day. To pay the bills. [sighs] Oh. Endless bills. What happened to my life?
Pastor Jeff: Orange wedge?

Sheldon: I may not look it, but I'm the future of physics, so just move on.