Sheldon: My first bathroom attempt. Let's hope this goes well.
Mary: Let me know if you need help.
Sheldon: I think I'll be okay. It's just number one.
Mary: I'm here if you need me.
[After Sheldon closes the bathroom door:]
Sheldon: [o.s.] Mom, I can't get my zipper down!
Mary: I'm coming.
Adult Sheldon: I am not saying my mother and I had a codependent relationship.
Sheldon: [o.s.] Mom, I can't get my zipper up!
Mary: I'm on my way!
Adult Sheldon: But she did have a tendency to baby me, and boy howdy, was I okay with that.

Adult Sheldon: I didn't realize until years later that my father was only asking questions about lightning and thunder to cheer me up. In fact, he would often pretend to be dumb just to make me feel better.

Adult Sheldon: My father didn't always get the credit he deserved. The advice he gave me actually worked out pretty well. Of course, I never told him.
George Sr.: Talked to Billy.
Missy: Why would you do that?
George Sr.: No, it was good.
Missy: Stay out of my life.
Adult Sheldon: He may not have been the world's greatest dad. But maybe we weren't the world's greatest kids.

Adult Sheldon: Visiting Tam's house for the first time was an emotional roller coaster.
For example, it's traditional in Vietnamese homes to have gruesome religious iconography near the entrance. I did not like that.
However, it's also customary to not wear shoes around the house for sanitary reasons. I did like that.
Interestingly, one of the main ingredients in Vietnamese cooking is an extremely pungent condiment known as fish sauce. I did not like that.
But before every meal, it's common for everyone to wash their hands and face. I did like that.
Forks are not customary in a Vietnamese household. I did not like that.
And instead of napkins, there was one towel for everyone to share at the table. Seriously, what are they thinking?

Meemaw: Look, you haven't even gotten to the worst part of it yet. They're gonna leave home. They're gonna move to another city.
Mary: Oh, Lord.
Meemaw: They're gonna tell you their loser boyfriend has knocked them up. Just to be clear, that would be you.
Mary: Sorry.
Meemaw: Turned my hair gray overnight.
Mary: I said sorry. Clearly, you're not in the mood to help.
Meemaw: Listen, it's hard being a parent, but if you do it right, they don't need you anymore.
Mary: Well, I don't like that. I get it, but I just don't like it.
Meemaw: Well, I'd point out, you'll always have your husband, but you want me to be "helpful".

Sheldon: Well, that's what I heard. And if Hawking doesn't let it stop him, then I can't let this cast stop me.
Missy: Great. Go back to sleep.
Sheldon: I will, and I'll do it all by myself. [sings] Soft kitty, warm kitty
Missy: Oh, my God.
Sheldon: Little ball of fur Happy kitty, sleepy kitty, purr Purr, purr.

George Jr.: "Have a great summer. Georgie". Normally I'd write, "Have a bitchin' summer", but I figured you wouldn't like that.
Sheldon: I wouldn't.