Sheldon: I guess I need to call and let him know what a bonehead mistake he made.
George Sr.: There's probably a nicer way to say it.
Sheldon: Did you hear how massive his neutrinos were? We're well into bonehead territory.
George Sr.: Sheldon, you don't need to be rude to him.
Sheldon: When am I rude?
[flashback to Sheldon watching a Missy combs the hair of her Cabbage Patch Doll:]
Sheldon: Stay a child as long as you can. Adulthood will not be kind to you.
[flashback to Sheldon looking at Meemaw's leg:]
Sheldon: Neat. The veins on your calf look like a road map of Texas.
[flashback to Sheldon at dinner time:]
Sheldon: Did you make this taste bad so Dad would lose weight?
[present:]
Sheldon: Fine. I'll be polite. But I still think we could go to San Antonio using Meemaw's leg.

Principal Petersen: Our next young speaker needs no introduction, but that didn't stop him from writing one and making me read it. [laughter] "Fun fact." [audience groans, murmurs] I hear you. "The word 'valedictorian' is from the Latin 'valedicere,' meaning 'to say farewell.' It is primarily used in the United States, Canada, the Philippines and Armenia." Maybe that fact's more fun in Armenia. Please welcome your valedictorian, Sheldon Cooper.
Mary: Yay, Shelly!
Sheldon: Hello. I'm not very comfortable speaking in front of crowds. But there's a technique to reduce stage fright by focusing on one person in the audience and delivering your speech just to them. That's what I'll be doing today. If it weren't for this person, I wouldn't be here right now. They've taught me a lot, and it's by their example that I found the courage to move forward into this new and exciting chapter of my life. Missy... ...this is for you. Change can be scary, but I know we're going to be fine... ...because like you said, "It's okay to be scared. We just have to do it anyway." So if any of my fellow graduates are nervous about the future, know that you're not alone. I suggest you all try to be as brave as my twin sister. That's my plan. Missy, I wish I could give you advice about middle school, but I was so smart, I skipped it. If you make it to high school, we'll talk. Thank you. [applause]

Missy: What's it like to not believe in God?
Sheldon: It's great. Big fan.
Missy: Are you ever afraid you're wrong?
Sheldon: About religion? Never. About other things? Also never.

Ms. MacElroy: Now, can anyone tell me why Melville shifts the narrative voice from Ishmael to Ahab? [Ms. MacElroy waits for somebody else to raise their hand] Sheldon.
Sheldon: I have a tummyache. I'd like to see the nurse.
Derek: A "tummyache"?
Sheldon: Yes, Derek, I have a tummy and it aches. Ergo, tummyache.
Derek: Ergo?
Sheldon: It's Latin, Derek.
Ms. MacElroy: Go to the nurse.
Sheldon: And to answer your question, the shifting point of view grants the reader a broader perspective of events than typically allowed by first-person narration.
Ms. MacElroy: Where were we?
Sheldon: And "ergo" is Latin for "hence," Derek.

Sheldon: Okay, here's the plan. End your relationship with Coach Ballard, date Dr. Sturgis again, get him to love you more than ever, then when he least expects it, break his heart and say, "That's for Sheldon."
Meemaw: Great plan.
Sheldon: You think so?
Meemaw: For the sake of this car ride, sure.

Adult Sheldon: Of all my many skills, one of the lesser known is my impressive ability to wait for things. I once stood perfectly still for 38 minutes because a bee was on my shoulder.
Sheldon: [blows, groans]
Adult Sheldon: I once waited four and a half hours to be released from a locker.
Sheldon: Hello? Anyone there? That's okay. I'll wait.
Adult Sheldon: And one time, when Dr. Sturgis was late for a lecture, I stayed longer than everyone.
Sheldon: Where are you all going?
Student: Professor's not here.
Sheldon: I can teach the class. I just need a box to stand on.

George Jr.: I bet the guy who invented the spork is a millionaire.
Jana: I guess.
George Jr.: I wonder if his last name is Spork.
Jana: It comes from "spoon" and "fork." Spork.
George Jr.: Oh, my God. Mind is blown.