Adult Sheldon: I didn't have to read many comic books to understand that every superhero had a weakness, something they had to overcome through an extraordinary act of courage. For Cyclops, it was the loss of Jean Grey. For Rogue, it was human touch. For me, it was food that required chewing. So if I truly was a mutant, I would have to do the same. On this day, I would not be defeated. Because this was the day I became The Chewer.

Adult Sheldon: I didn't realize until years later that my father was only asking questions about lightning and thunder to cheer me up. In fact, he would often pretend to be dumb just to make me feel better.

Adult Sheldon: My father didn't always get the credit he deserved. The advice he gave me actually worked out pretty well. Of course, I never told him.
George: Talked to Billy.
Missy: Why would you do that?
George: No, it was good.
Missy: Stay out of my life.
Adult Sheldon: He may not have been the world's greatest dad. But maybe we weren't the world's greatest kids.

Adult Sheldon: Ignoring things that irritate me isn't my strong suit. Obsessively fixating on them, now that's what gets me out of bed in the morning.

George: And Sheldon's fine. You know what he's like. If someone took him, I'm sure they'll bring him right back.

George: If we take him to a shrink, it feels like we're admitting something's wrong with him.
Mary: He hasn't had solid food in five weeks.
Meemaw: Well, if there is something wrong with him, it ain't constipation.

Missy: Meemaw, are you gonna have any more babies?
Meemaw: Good Lord, no!
Georgie: She's too old to have any more babies.
Meemaw: Don't have to have 'em. You live long enough, your hair and your teeth start falling out, you start wetting the bed, you get to be one.
Georgie: [laughs] That's funny. We're gonna have to put a diaper on you.
Meemaw: You won't be laughing when you're doing it. I might be.