Brenda Sparks: What do you want?
Mary: I baked you a pie.
Brenda Sparks: Why?
Mary: Well, I was thinking we haven't had the best history as neighbors.
Brenda Sparks: That's 'cause we don't like each other.

Mary: Shelly and this college stuff is killing me. I... I never went to college. How can I prepare him?
Brenda Sparks: Mary, if that kid is smart enough to have colleges wanting him already, he's got to be smart enough to figure it out.
Mary: Maybe. It still hurts to hear him say he wants to leave.
Brenda Sparks: I bet. On the other hand, I'm worried my Billy will never be ready to leave.
Mary: Oh, of course he will.
Brenda Sparks: Damn. Smoking, drinking, lying. You're covering all the sins today.

Mary: So, George is mad at me, and Sheldon is mad at me, and... honestly, I'm mad at me, too.
Brenda Sparks: Will you please give yourself a break? All that you do for that family, I am surprised you didn't crack years ago.
Mary: How do you handle it all?
Brenda Sparks: I'm sitting in a chicken coop drinking a wine cooler at 11:00 a.m.... clearly, I don't.

Mary: Hey, Brenda.
Brenda Sparks: She didn't want you to walk her in?
Mary: No. How about Billy?
Brenda Sparks: Oh, I walked him in. Found his homeroom. Explained that "homeroom" is different than his room at home. Still not sure he gets it.
Mary: Tough day.
Brenda Sparks: Yeah.
Mary: You want to get some coffee?
Brenda Sparks: I was thinking vodka, but coffee will do.

Sheldon: Do you believe there's intelligent life in the universe?
Dr. John Sturgis: I have no doubt.
Sheldon: Why is that?
Dr. John Sturgis: The Drake Equation claims that there are at least 20 detectable civilizations in our Milky Way galaxy alone.
Sheldon: Interesting. My sister likes to say that I'm an alien.
Dr. John Sturgis: I've often been called that. Once by the praying mantis in my dream.
Sheldon: Maybe we are aliens.
Dr. John Sturgis: Perhaps. Or maybe people like you and me were the original inhabitants of Earth, and everyone else is from outer space.
Sheldon: Ooh, I like that better.

Ms. Ingram: Mm-hmm. I'll tell him. Sheldon, you need to go to the principal's office.
Students: Ooh!
Sheldon: You do that every time. Why?

George Sr.: So what's this mean?
Principal Petersen: It means he pitched a perfect game, George. I've already gotten calls from colleges who want to meet him.
George Sr.: For, like, scholarships and stuff?
Principal Petersen: For everything! They might even pay you to get him.
George Sr.: My man!
Sheldon: When was the last time you washed your hands?
George Sr.: Come on!