Missy: How about a Houston Oilers cheerleader? "Signs point to yes." I'm gonna marry a quarterback.

George Sr.: What are you doing?
Missy: Watching Sheldon struggle with homework. It's so great.

Missy: So, this Dr. Lee is turning your friends against you?
Sheldon: Essentially.
Missy: Classic move. Most girls you find crying in the school bathroom, that was it.
Sheldon: What do I do?
Missy: Well, you're in a tough spot 'cause your personality is ugh.
Sheldon: There's enough people being mean to me right now.
Missy: Sorry.
Sheldon: Can you help me or not?
Missy: It's you against a bunch of college professors. I don't think you can win this one. [Sheldon starts to walk away] Oh. Do any of them have pimples?
Sheldon: No.
Missy: Too bad, I've done a lot of damage with "pizza face."

Mary: Bless us, Lord, for the food we are about to receive and bless the hands that prepared it.
Missy: And bless Mom.
Mary: Thank you. Amen.
Missy: Amen.
George Jr.: Amen.
Sheldon: She's the hands that prepared it. Your blessing is redundant.
Mary: Let's eat.

Adult Sheldon: I've fought many digital battles in my life, but none are as memorable as this first one with my Meemaw. By handing me the controller, she was telling me she believed in me. That inside my small, fragile frame beat the heart of a hero.

Adult Sheldon: Since that night, I've battled orcs, zombies, Nazis, Nazi-zombies, a dinosaur in a go-kart, and played Van Halen's "Hot for Teacher" on a stringless, plastic guitar. But nothing would ever compare to that first quest with my meemaw. Although Leonard pulling a groin muscle doing Dance Dance Revolution was a close second.

Adult Sheldon: Over the next few days, I ran to my Meemaw's house so we could save the 8-bit princess. And if it's unclear how important this was, let me say it again: I ran.