Sheldon: Good luck with your finger painting.
Missy: You're gonna get your ass kicked in high school.
Mary: (flicks Missy on the head) Hey!

Dale: So, how does this work?
Sheldon: You start by creating your character.
Missy: I want to be a Ninja Turtle Princess of Power.
Meemaw: Put me down for that, too.
Sheldon: You have to choose from one of the character classes. There's thief, druid, paladin, wizard...
Missy: Ooh, wizard. I want that.
Sheldon: All right.
Missy: Then I'll use my magic to turn me into a Ninja Turtle Princess of Power.
Sheldon: No.

George Sr.: What are you doing?
Missy: Watching Sheldon struggle with homework. It's so great.

Missy: So, this Dr. Lee is turning your friends against you?
Sheldon: Essentially.
Missy: Classic move. Most girls you find crying in the school bathroom, that was it.
Sheldon: What do I do?
Missy: Well, you're in a tough spot 'cause your personality is ugh.
Sheldon: There's enough people being mean to me right now.
Missy: Sorry.
Sheldon: Can you help me or not?
Missy: It's you against a bunch of college professors. I don't think you can win this one. [Sheldon starts to walk away] Oh. Do any of them have pimples?
Sheldon: No.
Missy: Too bad, I've done a lot of damage with "pizza face."

Mary: You understand that some people are going to be intimidated by you, because of how smart you are?
Sheldon: Or maybe they'll recognize my intellect and make me their leader.

Adult Sheldon: That was the first time I held my father's hand. I wouldn't touch my brother's hand until seventeen years later, thanks to the invention of Purell.

Sheldon: Per the student dress and grooming code, this boy's hair is too long. This boy's wearing sports attire outside a designated area. And this girl's blouse is diaphanous, which means I can see her brassiere.