Missy: I have to tell you something.
Dr. Sandra Thorpe: Why don't you finish the test first.
Missy: This can't wait. The other doctor's got a crush on you.
Dr. Sandra Thorpe: Oh, um I don't I don't think so. Let's get back to the test.
Missy: Okay.
Dr. Sandra Thorpe: Why? What did you see?
Missy: When you're not looking, he stares at your tushy.
Dr. Sandra Thorpe: [WHISPERING] Really?
Missy: Imagine if you wore the belt.

Missy: Eat dirt. Eat it.
Meemaw: Kick his ass!
Missy: Does it taste good? Huh?
Dale: Yeah, listen to your meemaw. Kick his ass!
Missy: You gonna cry? Huh? Do it. Cry.
Mary: Do something. Break it up.
George Sr.: H-Hang on. She's winning.
Mary: Missy! Missy Cooper, you stop beating up that boy!
Meemaw: Punch him in the nuts!

Missy: Someone's Underoos are in a knot.
Sheldon: My Underoos are fitting just fine, thank you.
Missy: Then why is there a stick up your butt?
Sheldon: Stop making inquiries about my bottom.
Missy: But I enjoy it.

[Sheldon sits on the top of the couch with his feet on the cushion]
Missy: What are you doing?
Sheldon: I'm practicing the philosophy of cynicism... The ancient Greek view that the rules of society should be ignored.
Missy: If you're gonna break rules, you can do better than that.
Sheldon: How?
[Missy pushes Sheldon off the couch]

Dr. John Sturgis: So, some colleagues of mine at the university are doing a research study on twins. I told them about Sheldon and his sister, and they were most intrigued.
George Sr.: Uh, what kind of study?
Dr. John Sturgis: It's a longitudinal investigation of environmental and genetic factors in the development of cognitive and other capacities in pairs of fraternal and identical twins.
Meemaw: You asked.

George Sr.: Listen, why don't we just go there this Saturday and give it a try?
Mary: And if you don't like it, we don't have to do it again.
George Sr.: Or they'll love it, and they'll do it till they're 18, 19 years old.
Sheldon: I already love it.
George Sr.: My man. Missy? I believe there might be a Dairy Queen on the way there.
Missy: Can I get an Oreo Blizzard?
George Sr.: You know what I think? I think you're smarter than him.

George Sr.: Well, geez, I don't I don't know if I want some scientists pokin' and proddin' the kids.
Meemaw: Oh, but they wouldn't be poked and prodded. They just have to, you know, answer some questions.
Dr. John Sturgis: And maybe some puzzles and tests.
George Sr.: That's not too bad. Where is it?
Dr. John Sturgis: Houston.
George Sr.: Oh, it just got bad. That's that's a long drive.
Dr. John Sturgis: It does pay $50 an hour plus gas and expenses.
George Sr.: Really?
Meemaw: I told you to start with that.