Missy: And I never would've agreed to the first friend if I knew the second friend was gonna call.
Meemaw: I think you know what you have to do.
Missy: What if it's one of those times where I actually have to make the mistake to learn from it?
[Missy exhales after Meemaw shoots her a unimpressed look]

Sheldon: Do people know about this?
Meemaw: Sheldon, what's on a person's face is not always what's in their heart.
Sheldon: Well, this changes everything. How do you know who to trust?
Meemaw: You don't. That's what makes life interesting.

George Jr.: Hey, now that you're treating him like an adult, can I have his allowance?
George Sr.: That allowance is for chores, which you already don't do.
George Jr.: Come on. We all know I'm your favorite.
Meemaw: You're not even his third favorite.

Mary: Mom, can you make the salad?
Meemaw: Sure.
George Sr.: Hey, don't put in any of those little tomatoes.
Meemaw: Hey, I don't tell you how to impersonate a lump of clay. You don't tell me how to make a salad.

Brenda Sparks: You friends with this girl?
Missy: [scoffs] I wish. She is so popular. One time she said she liked my outfit... I wore it for a week.
Brenda Sparks: [scoffs] What am I gonna do? [both sigh]
Missy: You could tell Billy he's too young to date.
Brenda Sparks: [chuckles softly] That's good. You might be the coolest person in this house.
Missy: Low bar, but thanks.

Sheldon: Dr. Linkletter, I need to talk to you.
Dr. Linkletter: Great.
Sheldon: Do you think you could get me access to the telescope room? I want to search for exoplanets that could support life.
Dr. Linkletter: Are you feeling homesick?
Sheldon: Are you implying that I'm from another planet?
Dr. Linkletter: Yes.
Sheldon: Compliment accepted.

Sheldon: Dr. Linkletter, I need to talk to you.
Dr. Linkletter: Are we in my office?
Sheldon: No.
Dr. Linkletter: Then these are not my office hours.
Sheldon: Are you using my love of schedules against me?
Dr. Linkletter: [chuckles] Oh, yes.
Sheldon: Well done.