Sheldon: You like boys, and you're half an inch taller than me now.
Missy: It's called growing up.
Sheldon: Well, I don't like it.
Missy: Trust me, 20 years from now you're not gonna be sitting around, talking about Star Trek and reading comic books.
Sheldon: Would you like to bet on that?
Missy: A dollar.
Sheldon: Hmm. [they pinky swear]
Adult Sheldon: [v.o.] She still hasn't paid me. And guess who's wearing Star Trek underpants right now.

Mary: Missy, if you want a minute with Dad before they close the casket, now's the time. [Missy looks unsure] It's okay if you don't.
Mary: I have to. [Missy stands up and walks up to her father's casket]
[flashback:]
George: Here, let me help you with that. Okay.
Missy: [eats] Holy moly.
George: It's good, huh?
Missy: Unbelievable.
George: I'll leave you to it.
Missy: No, sit with me.
George: Okay.
[present:]
Missy: [crying] Thank you for that. Thank you for everything. [sniffles] I love you.

Sheldon: Is Mom okay?
George: How the heck should I know?
Missy: She left. You can say "hell."

Dr. Sandra Thorpe: Have you always been that way?
Missy: I guess so. I think when you're on your own a lot, you get good at seeing that kind of stuff.
Dr. Sandra Thorpe: Really?
Missy: My dad does football with my older brother, so they're like a team. And my mom and meemaw spend all their time fussing over Sheldon, so they're like a team, too.
Dr. Sandra Thorpe: So no one's on your team?
Missy: Nope. It's just me.

Mary: You are right. You have been here longer than me. I don't see why we can't work together.
Peg: That'd be nice.
Mary: Great. So, why don't you go by the bank, and I will drop off the bulletin?
Peg: So no one's gonna answer the phones?
Mary: Fine. You just sit there, and I'll go and do everything.
Peg: Sweet. Oh, today's a stumper. Is "nipto" a word?
Mary: You know what? This is why I was taking charge of everything. Because if I don't, nothing will get done.
Peg: Oh, it's "pinto". [laughs]
Mary: This is exactly what I'm talking about.
Peg: Guess what, Mary. Things were getting done long before you got here.
Mary: I just want everything taken care of for Pastor Jeff.
Peg: Or you just like thinking you're better than everybody.

Pastor Jeff: Isn't he the cutest?
Mary: He sure is.
Peg: Oh.
Pastor Jeff: Yeah, he's an angel. He's just happy all the time... morning, afternoon, middle of the night, 2:00a.m., 3:00a.m., all the a.m.'s, really.
Peg: Dip the pacifier in some whiskey, put him right out. But don't use the good stuff. They can't tell the difference.

Sheldon: Why are you taking that down?
Missy: It's time to grow up.
Sheldon: Leave it there.
Missy: You don't even like Cyndi Lauper.
Sheldon: No, but it's part of my daily routine. Every morning I wake up, look over there and wonder, "Why is she standing like this?"
Missy: Too bad. It's my room.
Sheldon: It's my room, too.
Missy: Yeah, and I don't get a say in any of your stupid posters.
Sheldon: These are the smartest men who ever lived, so if anyone's stupid, it's you for saying that.
Missy: Shut up!
Sheldon: You're very irritable. This might be why you're having boy problems.