[on the "Why Sheldon Cooper Should Go to College" tape:]
Ms. MacElroy: I don't think I have anything left to teach Sheldon. I'm pretty sure he's already smarter than me.
Sheldon: It's true.

Ms. MacElroy: That's sweet of you for asking, but I'd rather stick my finger in a pencil sharpener and crank away.

Ms. MacElroy: Tell you what I do. I send him on little errands. Like the other day, I told him, "Go to the supply room and get me a framastan."
Coach Wilkins: What's a "framastan"?
Ms. MacElroy: No such thing. I made it up. He was gone the whole period.
Ms. Ingram: [laughs] I'm using that.
Ms. MacElroy: Don't use "framastan". That's mine.

Ms. MacElroy: Georgie Cooper?
Georgie: Here.
Ms. MacElroy: Sheldon Cooper? Georgie, where's your brother?
Georgie: I don't know.
Ms. MacElroy: Good enough for me.

Mary: So, George is mad at me, and Sheldon is mad at me, and... honestly, I'm mad at me, too.
Brenda Sparks: Will you please give yourself a break? All that you do for that family, I am surprised you didn't crack years ago.
Mary: How do you handle it all?
Brenda Sparks: I'm sitting in a chicken coop drinking a wine cooler at 11:00 a.m.... clearly, I don't.

[on the "Why Sheldon Cooper Should Go to College" tape:]
Ms. Ingram: Honestly... teaching Sheldon is the hardest thing I've ever had to do. And I don't say that because he can be a pain. I say that because he's so intelligent, I had to study every night just to keep up. I'm gonna miss him.

George: What do you want, Sheldon?
Sheldon: I want to know why no one told me about this recruitment letter from Caltech.
George: Let me see that.
Mr. Givens: All right, let's get me drunk.
Sheldon: Hi, Mr. Givens.
Mr. Givens: Aw, come on!