George Sr.: All right, here's the deal. My kid's got a damn ulcer 'cause of you, so either you take him seriously, or you're gonna be taking me seriously. [INTERCOM BUZZES]
Mrs. Veazey: Yes, sir?
Dr. Hodges: Janice, why don't you send the little boy in? Right away.

Dr. Hodges: I'll tell you what. Here is a NASA patch. Why don't you have your mom sew that on your book bag?

Dr. Hodges: Now, who here wants to know how astronauts go to the bathroom?
Boy: Me. I do.
Dr. Hodges: Oh, right. See, now, during liftoff, all the astronauts wear diapers.

Dr. Hodges: Yeah, perhaps when Captain Kirk said, "To boldly go," he meant in one of those, huh? Yeah, that's right. Beam me up, Potty!

George Sr.: Damn it. I've had enough of this. Sheldon, get up.
Sheldon: What's the point?
George Sr.: We're going to Houston.
Sheldon: Really?
George Sr.: Yeah. You and me are gonna give those space monkeys a little talkin' to.
Adult Sheldon: I often found my father to be a strange and puzzling man, but at that moment, I never loved him more.

Adult Sheldon: People often wonder why I chose to pursue a career in theoretical physics. I usually respond by saying I wanted to unravel the inner workings of the universe. But the real answer was I wanted to prove this nincompoop wrong.

George Jr.: Are you dyin'?
Meemaw: We're all dyin', honey. From the second we're born, it's just a slip and slide into the darkness.
George Jr.: Unless you get bit by a vampire.
Meemaw: Well, now that goes without saying.