Adult Sheldon: People often wonder why I chose to pursue a career in theoretical physics. I usually respond by saying I wanted to unravel the inner workings of the universe. But the real answer was I wanted to prove this nincompoop wrong.

Adult Sheldon: I didn't realize until years later that my father was only asking questions about lightning and thunder to cheer me up. In fact, he would often pretend to be dumb just to make me feel better.

Adult Sheldon: Ignoring things that irritate me isn't my strong suit. Obsessively fixating on them, now that's what gets me out of bed in the morning.

Adult Sheldon: My father didn't always get the credit he deserved. The advice he gave me actually worked out pretty well. Of course, I never told him.
George: Talked to Billy.
Missy: Why would you do that?
George: No, it was good.
Missy: Stay out of my life.
Adult Sheldon: He may not have been the world's greatest dad. But maybe we weren't the world's greatest kids.

Meemaw: So I saw a lawyer today.
Mary: Why?
Meemaw: I'm putting together my last will and testament.
George: We're gonna miss ya.
Mary: George.
Meemaw: Don't worry. I ain't leaving him squat.

Mary: Sheldon, who are you talking to?
Sheldon: Dorothy Fitzpatrick.
Mary: Who's Dorothy Fitzpatrick? Is she a new buddy from school?
Sheldon: She's the loan officer at The First National Bank of Medford.
Mary: Why are you talking to her?
Sheldon: Mom, can this wait? I'm trying to negotiate favorable terms. Hello, Dorothy? [Mary hangs up]

Georgie: Are you dyin'?
Meemaw: We're all dyin', honey. From the second we're born, it's just a slip and slide into the darkness.
Georgie: Unless you get bit by a vampire.
Meemaw: Well, now that goes without saying.