Mary: Now, come on, let's tuck you in.
Missy: I'm glad I don't have orange hair.
Mary: Me, too, baby.
Missy: I want to be more like Madonna.
Mary: Are you trying to kill me? 'Cause if you are, good job.
Missy: Why is she only like a virgin?
Mary: Good night!

George Sr.: What are you doing?
Missy: Watching Sheldon struggle with homework. It's so great.

Missy: So, this Dr. Lee is turning your friends against you?
Sheldon: Essentially.
Missy: Classic move. Most girls you find crying in the school bathroom, that was it.
Sheldon: What do I do?
Missy: Well, you're in a tough spot 'cause your personality is ugh.
Sheldon: There's enough people being mean to me right now.
Missy: Sorry.
Sheldon: Can you help me or not?
Missy: It's you against a bunch of college professors. I don't think you can win this one. [Sheldon starts to walk away] Oh. Do any of them have pimples?
Sheldon: No.
Missy: Too bad, I've done a lot of damage with "pizza face."

Mary: Bless us, Lord, for the food we are about to receive and bless the hands that prepared it.
Missy: And bless Mom.
Mary: Thank you. Amen.
Missy: Amen.
George Jr.: Amen.
Sheldon: She's the hands that prepared it. Your blessing is redundant.
Mary: Let's eat.

Adult Sheldon: I didn't realize until years later that my father was only asking questions about lightning and thunder to cheer me up. In fact, he would often pretend to be dumb just to make me feel better.

Adult Sheldon: I never did get to see a launch in person, but that was the best trip I ever had. I wish I had told my father while he was alive.

Mary: Wait, Georgie. Where's your bag?
George Jr.: Don't need one. Got my toothbrush right here.
Mary: What about clothes? A change of underwear?
George Jr.: Got it.
Mary: Georgie, you're gonna be gone for two days.
George Jr.: I'll turn them inside out.