Adult Sheldon: Not since sharing a uterus with my twin sister have I been so unhappy sitting next to someone.

Adult Sheldon: I didn't realize until years later that my father was only asking questions about lightning and thunder to cheer me up. In fact, he would often pretend to be dumb just to make me feel better.

Adult Sheldon: My father didn't always get the credit he deserved. The advice he gave me actually worked out pretty well. Of course, I never told him.
George: Talked to Billy.
Missy: Why would you do that?
George: No, it was good.
Missy: Stay out of my life.
Adult Sheldon: He may not have been the world's greatest dad. But maybe we weren't the world's greatest kids.

Adult Sheldon: Ignoring things that irritate me isn't my strong suit. Obsessively fixating on them, now that's what gets me out of bed in the morning.

Dr. John Sturgis: Did you know that there's a type of vanilla flavoring derived from the anal glands of the North American beaver?
Meemaw: That seems like a fact you could have shared before we started eating.
Dr. John Sturgis: It isn't used very often. I understand it's difficult to, uh, milk the little sacs.
Meemaw: Cool. Okay, new topic.

Dr. John Sturgis: See, this is why we're great together. You teach me about social etiquette, and I teach you about beaver anuses.
Meemaw: [CHUCKLES] It is magical.
Dr. John Sturgis: Did you know "ani" is also acceptable as the plural of "anus"?
Meemaw: And the magic continues.

Paige: You actually believe in the multiverse theory?
Sheldon: Very much so. It's the most elegant interpretation of quantum mechanics.
Paige: So you really think there are an infinite number of universes?
Sheldon: Stephen Hawking believes it, so, yes, I do.
Paige: Well, if there are an infinite number of universes, I think that theory's dumb in all of them. [CHUCKLES] This is fun.