Mary: We're real proud of you, honey.
Missy: Are you proud of me and Georgie?
Mary: Of course.
George Sr.: You bet.
George Jr.: For what?
Meemaw: Don't go pokin' at it.

Sheldon: Dad?
George Sr.: Yeah?
Sheldon: Thank you.
George Sr.: You're welcome.

Adult Sheldon: I've often contemplated what might have happened if my father hadn't stuck up for me that day. Would I have gone on to become a world-class theoretical physicist, or just your average Joe Sixpack theoretical physicist?

Dr. Hodges: This is groundbreaking work. Thank you.
Sheldon: And?
Dr. Hodges: And?
Sheldon: I thought you might want to apologize.
Dr. Hodges: Well why?
Sheldon: You tried to shut me up with a patch.
Dr. Hodges: Well, I-I give those to everyone. A-And you have to understand, Sheldon, that while your math is-is theoretically correct, we don't have the technical capability to execute it.
Sheldon: So I'm ahead of my time?
Dr. Hodges: Well it would appear so.
Sheldon: All right, call me when you catch up.

George Jr.: I'm bored.
Missy: Me, too.
Meemaw: Hey. Someday somebody's gonna write a book about Sheldon. Don't you want there to be a chapter about how loving and supportive you two were?
George Jr.: Doesn't matter. I ain't reading it.

George Sr.: Oh, he's been in there quite a while.
Mary: Well, if the topic is science, he can be a real Chatty Patty.

Dr. Hodges: Anything else?
Sheldon: Yes. I'd like a glass of water. It's time to take my Zantac.

Sheldon: And here near apogee, we gimbal the engine to exert a torque that executes a pitchover maneuver to flip the rocket by 180 degrees.
Dr. Hodges: Well, that's very impressive. Thank you very much for taking the time-
Sheldon: I'm not done.
Dr. Hodges: Uh, sorry.

George Sr.: All right, here's the deal. My kid's got a damn ulcer 'cause of you, so either you take him seriously, or you're gonna be taking me seriously. [INTERCOM BUZZES]
Mrs. Veazey: Yes, sir?
Dr. Hodges: Janice, why don't you send the little boy in? Right away.

George Sr.: Yeah, I don't mean to be rude, but we've been waitin' for an hour to see your boss.
Mrs. Veazey: I'm sorry, sir, but you didn't have an appointment.
George Sr.: We didn't have an appointment 'cause every time I called, you put me on hold.

Missy: Oh, God, it's on my shoes, it's on my shoes!
Meemaw: For Pete's sake, somebody open a window.

George Jr.: I don't see why I couldn't stay home.
Mary: 'Cause we're having a fun family outin'.
George Jr.: Can I at least drive?
Meemaw: She said fun, not tragic.

George Sr.: Damn it. I've had enough of this. Sheldon, get up.
Sheldon: What's the point?
George Sr.: We're going to Houston.
Sheldon: Really?
George Sr.: Yeah. You and me are gonna give those space monkeys a little talkin' to.
Adult Sheldon: I often found my father to be a strange and puzzling man, but at that moment, I never loved him more.

Adult Sheldon: With my research complete and my ulcer on the mend, all that was left to do was send my work to NASA and wait to become America's scientific sweetheart.

Missy: Mom.
Mary: What?
Missy: There's something wrong with Sheldon again.
Sheldon: I figured it out! I figured it out!
George Sr.: One night. I want to sleep one night.

Mary: Sheldon! What are you doing?
Sheldon: I just need a minute. These things are so slow. [to Dr. Eberland] Is this your family? They're lovely.

Dr. Eberland: Okay. Well, keep him off spicy foods for the time being, and I'll write you a prescription for Zantac. Does he smoke?
Mary: 'Course not. He's nine.
Dr. Eberland: [chuckles] I started at his age. Uh, but only when I drank.

Dr. Eberland: Um, Radio Shack?
Mary: He's trying to figure out how to help NASA land rockets.
Dr. Eberland: Oh. Well, that's a nice thing.
George Sr.: He's just doing it out of spite.

George Sr.: Go!
Sheldon: And you're surprised I have an ulcer.
George Sr.: I'm surprised I don't have one.

Sheldon: I've heard some interesting research about treating ulcers with antimicrobials.