Dr. Bowers: Okay, Sheldon, we're gonna put the mask on. Now you just breathe normally and count back from 100.
Sheldon: But counting back from 100 isn't complex enough to occupy my mind.
Dr. Bowers: You're up again.
Mary: Why don't you think of something more sciencey? Like counting pi. That's a thing, right? Pi?
Sheldon: I can't count pi, it's an irrational number. But I can embrace the spirit of your proposal and calculate the matrix coefficients necessary for a unified field theory.
Dr. Bowers: Do that. Hit it.
Sheldon: [slurring] Of the four fundamental forces, the most difficult to unify is gravity because...
Dr. Bowers: Oh, thank God.

Principal Petersen: Our next young speaker needs no introduction, but that didn't stop him from writing one and making me read it. [laughter] "Fun fact." [audience groans, murmurs] I hear you. "The word 'valedictorian' is from the Latin 'valedicere,' meaning 'to say farewell.' It is primarily used in the United States, Canada, the Philippines and Armenia." Maybe that fact's more fun in Armenia. Please welcome your valedictorian, Sheldon Cooper.
Mary: Yay, Shelly!
Sheldon: Hello. I'm not very comfortable speaking in front of crowds. But there's a technique to reduce stage fright by focusing on one person in the audience and delivering your speech just to them. That's what I'll be doing today. If it weren't for this person, I wouldn't be here right now. They've taught me a lot, and it's by their example that I found the courage to move forward into this new and exciting chapter of my life. Missy... ...this is for you. Change can be scary, but I know we're going to be fine... ...because like you said, "It's okay to be scared. We just have to do it anyway." So if any of my fellow graduates are nervous about the future, know that you're not alone. I suggest you all try to be as brave as my twin sister. That's my plan. Missy, I wish I could give you advice about middle school, but I was so smart, I skipped it. If you make it to high school, we'll talk. Thank you. [applause]

Mary: Sheldon, faith means believing in something you can't know for sure is real. And right now, I am struggling with that.
Sheldon: So you don't believe in God anymore?
Mary: That isn't something for you to worry about. I need to figure this out myself.
Sheldon: Can I help? Maybe I could provide a fresh perspective.
Mary: I don't think so, baby.
Sheldon: Did you know that if gravity were slightly more powerful, the universe would collapse into a ball?
Mary: I did not.
Sheldon: Also, if gravity were slightly less powerful, the universe would fly apart and there would be no stars or planets.
Mary: Where you going with this, Sheldon?
Sheldon: It's just that gravity is precisely as strong as it needs to be. And if the ratio of the electromagnetic force to the strong force wasn't one percent, life wouldn't exist. What are the odds that would happen all by itself?
Mary: Why are you trying to convince me to believe in God? You don't believe in God.
Sheldon: I don't, but the precision of the universe at least makes it logical to conclude there's a creator.
Mary: Baby, I appreciate what you're trying to do, but logic is here. And my problem is here.
Sheldon: Well, there are 5 billion people on this planet and you're the perfect mom for me. What are the odds of that?

Missy: What's it like to not believe in God?
Sheldon: It's great. Big fan.
Missy: Are you ever afraid you're wrong?
Sheldon: About religion? Never. About other things? Also never.

Sheldon: So none of you can help me?
Albert Einstein: I believe I can. Sheldon, if I was offered a choice between all the knowledge of the universe or the endless pursuit of it, I would choose the pursuit.
Sheldon: That's very insightful.
Richard Feynman: Hold it, hold it... He didn't come up with that! He stole it from Gotthold Lessing.
Professor Proton: Who's-who's Gotthold Lessing?
Cyndi Lauper: [v.o.] He's an 18th century German philosopher. Now do you mind? We girls are trying to have some fun over here.
Einstein: Apologies.
Richard Feynman: Sorry, Cyndi Lauper.
Stephen Hawking: Our bad.
Professor Proton: I-I like fun.

Ms. Hutchins: Hi, Sheldon, what can I do for you?
Sheldon: Do you have any books or videos on the Lamaze technique?
Ms. Hutchins: Uh-oh. Georgie get that girl pregnant?
Sheldon: It's for me. I need to have a tooth pulled, and I'd like to do it without putting my brain on drugs.
Ms. Hutchins: Okay.
Sheldon: I've seen that commercial with the egg in the frying pan. Very effective.

George Jr.: Can I at least change the music we play here?
Dale: What's wrong with the music we play here?
George Jr.: Nothing, it's just kind of grandpa music.
Dale: Well, how is this "grandpa music"?
George Jr.: Do you listen to it?
Dale: Yeah.
George Jr.: Do you have grandchildren?
Dale: Yeah.
George Jr.: Do you see where I'm going with this?