Missy: Hey, Mom, can Paige sleep over this weekend?
Mary: I guess, if her mother says okay.
Sheldon: Wait, where is she going to sleep?
Missy: In your bed. You can sleep on the couch.
Sheldon: Absolutely not. I've already changed my brand of loafers, I am not changing my sleeping quarters.

Missy: Did you guys know Paige speaks three languages?
Meemaw: Really? That's impressive.
Missy: You only speak one.
Sheldon: Two. I'm learning conversational Klingon.

Missy: 95, 96, 97. 99, 100.
Sheldon: You missed 11 numbers.
Missy: I don't need to be good at math. I have beautiful hair.
Sheldon: That's the saddest thing I've ever heard.

Meemaw: There are certain grown-up dynamics taking place here that you, you might not be aware of.
Sheldon: Well, I like quantum-chromodynamics and thermodynamics; perhaps I'll like grown-up dynamics. Tell me.
Meemaw: I'm just saying that Dr. Linkletter might be paying special attention to you so he can become better friends with me.
Sheldon: Why?
Meemaw: You're just gonna have to trust me on this one.
Sheldon: Are you saying he doesn't really want me at this lecture?
Meemaw: No, I'm just saying he really wants me at this lecture.
Sheldon: But that's illogical. He knows you're in a relationship with Dr. Sturgis.
Meemaw: And now we're back to it's complicated, so drop it.
Sheldon: I'll try, but dropping things is not where I shine.

George Sr.: Sheldon, I'm talking to you.
Sheldon: Well, I'm not talking to you.
George Sr.: Okay, what's going on?
Sheldon: After having my first good night's sleep in a week, I woke up with a fresh perspective.
George Sr.: And that is?
Sheldon: It was irresponsible of you to burden me with that secret.
George Sr.: Sheldon, we've been through this. It's complicated.
Sheldon: While I may not look up to you from an intellectual standpoint, I've always looked up to you as a role model. I can't do that anymore. And don't worry, we made a deal. I'll continue to keep your secret.

Sheldon: I can't remember what the zeroes of the Bessel function are.
Dr. Linkletter: You didn't memorize them?
Sheldon: Of course I did... October 7th, 1988. I had just had a bowl of Teddy Grahams.
Dr. Linkletter: Then what's the problem?
Sheldon: I'm blanking, but I'll get it.
Dr. Linkletter: Sorry, son, class is over.
Sheldon: No, I can do this.
Dr. Linkletter: It's just one question. You'll still pass.
Sheldon: Sheldon Cooper doesn't "just pass."
Dr. Linkletter: I have an idea. Let me see the test. [Sheldon hands him the test] Thank you.
Sheldon: Sheldon Cooper isn't always that gullible.
Dr. Linkletter: He was today.

Sheldon: Missy! You gave me your yips.
Missy: What?
Sheldon: I froze on a test. That's never happened before. It's all your fault.
Missy: I told you it's not contagious.
Sheldon: You put the thought in my head. The power of suggestion is very real. Case in point: tulip mania.
Missy: Here we go.
Sheldon: Tulip mania was an insane desire to buy and trade tulip bulbs in the 1600s. It nearly ruined the Dutch economy. You would not believe the gilders they were spending.

Sheldon: Are we sleeping there? Do I need to bring pajamas?
George Jr.: Just sleep in your underwear.
Sheldon: In my underwear? I hardly think so.

Mary: Sweet dreams. Love you.
Sheldon: Love you, too, 'cause you're my mom. [LAUGHS NERVOUSLY]

Mary: So how's it going?
Sheldon: Well, the principles in the book didn't work for me at all. Although Dad does like being called George over and over again, so you might give that a try.

George Sr.: Well, a couple of scientists at the college where Dr. Sturgis teaches are doing a research study on twins. They want to meet you guys, ask you some questions.
Sheldon: Oh, boy, a research study. Will they give us written tests?
George Sr.: Yeah, I think so.
Sheldon: Oh, boy.

Sheldon: Should I go left or right?
Meemaw: Why don't you try going in that cave?
Sheldon: Why would I do that? It's probably dangerous.
Meemaw: Sheldon, they wouldn't have put the cave there if they didn't want you to go in it.
Sheldon: Seems unnecessarily reckless, but okay. "Dark and dangerous." I told you.
Meemaw: Just keep going.
Sheldon: The box was right, my heart is pounding.

Meemaw: Why don't you let the old person give it a shot?
Sheldon: Would you like me to give you a tutorial first?
Meemaw: Give it to me. I'll figure it out.
Sheldon: We are such different people, Meemaw.

Tam: I don't understand why it didn't launch.
Sheldon: Me, neither. Evil Nazi scientists did it 50 years ago. How hard could it be?

Sheldon: I also found us extra life points inside a demon.
Mary: There are demons in this game?
Sheldon: Don't worry, Meemaw cut his head off.

Sheldon: [choking] There's lemon in this water.

Dr. Linkletter: [answers phone] Hello?
Sheldon: Can I be your lab assistant?
Dr. Linkletter: What time is it?
Sheldon: That's not a no.
Dr. Linkletter: If I say yes, will you please stop hounding me?
Sheldon: Absolutely.
Dr. Linkletter: Fine. You win. Good night.
Sheldon: Just out of scientific curiosity, were you persuaded by the disorienting nature of this late-night phone call or by the cumulative weight of my relentlessness?
Dr. Linkletter: That one. [hangs up]
Adult Sheldon: I learned an important lesson that night. When you want something, relentlessly annoying is your road to victory.

Zero: Shall we give him the final piece of information that unlocks the secret of the universe?
One: Why not? At least one human being should know the reason for everything.
Zero: Sheldon, before the universe began-
George Jr.: Hey, dummy. You're drooling all over your books.
Sheldon: Huh? No. Zero was about to tell me the secret and you ruined it.

Sheldon: (to George Sr.) Why would you think you knew his mom?

Dr. John Sturgis: It's so good to see you.
Sheldon: I don't normally do this, but put her there.
Dr. John Sturgis: No mitten. I'm honored.