George Sr.: All right, see, when you get tackled in your own end zone, the other team gets two points and the ball. That's called a safety.
Missy: I thought one of the players was a safety.
George Sr.: Well, that's true, too.
Missy: I'm confused.
George Sr.: Now you know how I feel when you talk about Teenage Mutant Ninja Turtles.
Missy: What's confusing? Everything you need to know is in the title.

George Sr.: What are you doing?
Missy: Watching Sheldon struggle with homework. It's so great.

Missy: So, this Dr. Lee is turning your friends against you?
Sheldon: Essentially.
Missy: Classic move. Most girls you find crying in the school bathroom, that was it.
Sheldon: What do I do?
Missy: Well, you're in a tough spot 'cause your personality is ugh.
Sheldon: There's enough people being mean to me right now.
Missy: Sorry.
Sheldon: Can you help me or not?
Missy: It's you against a bunch of college professors. I don't think you can win this one. [Sheldon starts to walk away] Oh. Do any of them have pimples?
Sheldon: No.
Missy: Too bad, I've done a lot of damage with "pizza face."

Mary: Bless us, Lord, for the food we are about to receive and bless the hands that prepared it.
Missy: And bless Mom.
Mary: Thank you. Amen.
Missy: Amen.
George Jr.: Amen.
Sheldon: She's the hands that prepared it. Your blessing is redundant.
Mary: Let's eat.

Mary: I was just letting you know that if you were having any problems you could come to me with them.
Sheldon: You think I have mental problems?
Mary: Well, not problems. I'm just worried about your future, and when I see you moving subatomic particles around in the air, that makes-
Sheldon: Subatomic particles are real! You talk to an invisible man in the sky who grants wishes. If anyone's mental, it's you.

Sheldon: [to Mary] I am behaving no differently than I ever have. Why are you suddenly so worried about me?
Dr. Goetsch: That is a valid question. Has anything changed recently?
Sheldon: Maybe it's hormonal. When does menopause typically begin?
Mary: It is not my hormones.
Sheldon: Well, it certainly isn't mine. I'm showing no signs of puberty.

Sheldon: Mother?
Mary: Yes?
Sheldon: Is it okay if I use a knife to butter my toast, or are you worried I'll do something crazy with it?
Mary: You can butter your own toast.
Sheldon: Oh, good. You see the toast, too. I was afraid I was imagining it.