George Sr.: Oh, yeah. Connie's great. You can have a beer with her, watch a football game, joke around. She doesn't mind if you swear. In fact, that woman's got a mouth on her.
Dale: I have noticed that.
George Sr.: Yeah. You know, I just realized something. I got more in common with my mother-in-law than I do my own wife.
Dale: That's kind of creepy.
George Sr.: Yeah. Let's hope the beer does its job and I don't remember this tomorrow.

George Sr.: And Sheldon's fine. You know what he's like. If someone took him, I'm sure they'll bring him right back.

Sheldon: There's going to be a lecture on carbon dating at the Natural Science Museum on Saturday. Who would like to take me?
George Sr.: You know what? I'd be happy to.
Meemaw: What happened to helping me at my yard sale?
George Sr.: Ooh, is that this Saturday? I'm sorry. I'm taking him to a lecture on, uh what is it? Carbonation?
Sheldon: Carbon dating. A method of determining the age of artifacts and fossils.
George Sr.: Hey, we could use that to figure out how old your grandma is.
Sheldon: That won't work. You can't carbon-date something that's alive.
George Sr.: Well, then, we'll just chop her down and count the rings.
Meemaw: Oh, George, did my "lump of clay" remark strike a nerve?
George Sr.: A little.

Meemaw: I bowled a new high score last night.
George Sr.: Nice.
Meemaw: I got two turkeys.
Missy: What's a turkey?
Meemaw: It's three strikes in a row.
Missy: Why do they call it a turkey?
Meemaw: Well, when they first invented bowling, they used to just throw frozen turkeys at the pins. Eventually, they switched to balls to cut down on the smell.
George Sr.: Why you lying to her?
Meemaw: I find it keeps my mind sharp.

Lisa: [modem screeching] What's that noise?
George Jr.: No idea.
Sheldon: Georgie, I need you to get off the phone.
George Jr.: Hang on, Lisa. I'm helping someone with their English homework.
Sheldon: I don't have time for jokes. I need the phone line to connect my modem.
George Jr.: What the hell's a modem?
Sheldon: It links my computer to an interconnected web of other computers in order to facilitate the exchange of ideas.
George Jr.: That's the stupidest thing I've ever heard of.
Adult Sheldon: Sadly, that was not the stupidest thing he ever said.

Adult Sheldon: Thanks to Dr. Sturgis, I had all the intellectual ammunition I needed to bring my opponent to his knees. I accused him of conflating two different interpretations of quantum theory, woefully misrepresenting Paul Dirac, and when I called him a dung beetle in Latin, I was so riled up, I almost started producing testosterone.

Dale: Have you tried the meatballs here? They are fantastic.
Meemaw: I haven't. But speaking of meatballs, I hear you're gonna hang out with my son-in-law.
Dale: Yeah.
Meemaw: Hmm.
Dale: Oh. You don't like that at all.
Meemaw: No, it's fine with me. I hope you all go out and have a grand old time.
Dale: Oh. Yeah, well, what's the matter? You afraid I'm gonna find out all your secrets?
Meemaw: Calm down. You're enjoying this a little too much.
Dale: Enjoying it? I'm loving it. Look how mad you're getting. Come on, what's he got on you? Did you do some jail time? Were you a go-go dancer?
Meemaw: Hmm.
Dale: Have you got a tattoo in a naughty place? Can I see it?